Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health

自工业革命以来,全球气温已经上升了0.8摄氏度。虽然去年1摄氏度的升温不太可能在今后每年都出现,但科学家表示由于厄尔尼诺事件的持续,2016年可能又将是一个极端炎热的年份。
他认为,地方政府通过卖地、强拆来追求GDP代价太大,早晚要还。“我愿意用一个政协委员的身份非常严肃地提出问题,我们是不是可以不要那么重视GDP?我们是不是可以选择减缓经济发展的速度?”
The official non-manufacturing PMI came in at 54.3 in October, down from a recent peak of 55.4 a month prior. A key sub-index for the services sector likewise fell 0.9 points from its September peak to 53.5. Even the construction industry appeared worse off, with a sub-index for the sector dropping 2.6 points to 58.5.
今年上榜的十亿美元级富豪为1810名,低于去年1826人的记录。上榜富豪净资产总计为64800亿美元,比去年减少了5700亿美元。
n. 比赛,竞争,竞赛
Critics have been eager to point out that he is not so closely involved in new product development as his predecessor, and fails to elicit the same excitement when he takes to the stage to introduce them. But Mr Cook is aware of his shortcomings and has drawn on the worlds of fitness and fashion to assemble a new team of talents, including Angela Ahrendts, formerly of Burberry, and industrial designer Marc Newson.
在接受《每日电讯报》采访时,玛蒂说:“我再也无法过上平凡人的生活了。因为大家很容易认出我来,甚至当我出去玩或是和朋友吃冰淇淋都能被路人认出来。”
In this April 24, 1984, file photo, from left, Steve Jobs, chairman of Apple Computers, John Sculley, president and CEO, and Steve Wozniak, co-founder of Apple, unveil the new Apple IIc computer in San Francisco
抵达太阳系深处的人类智慧。
She argues, however, that the problems with lower liquidity of ETFs in Asia are a symptom of a fund distribution system that fails to incentivise ETF sales by intermediaries. “I don't think there is a quick fix, but you would see a pick-up if Asia moves to a fee-based model,” she says.
['elim?nt]
There are 15 Chinese brands in the top 100, one more than last year and a sharp rise on a decade ago, when China Mobile was the only Chinese brand.
Transport Ministry spokesman Xu Chengguang told a news conference that no further signs of life had been found and the chance of finding anyone else alive was "very slim."
在这个被大型地产开发商主宰的市场,结构性挑战通常成为抑制欧美大型资产管理公司的因素。
Promoting employment should be prioritized, said Premier Li Keqiang at a meeting organized by the Ministry of Human Resources and Social Security on last Friday.
10月份,日本生产增长速度突然提升,让决策者对日本经济的实力有了更多希望,或许也可以理解为释放了更多喜忧参半的信号。
和许多评论家一样,我一方面了解清单的便利,一方面也讨厌清单的专横。所以我永远不可能只列出十部――我怎么做得到呢,北美影院一年就要上映900多部影片呢――今年是2015年,所以我挑选了15部,为它们分门别类,计数时做了一点含糊,所以最后其实是20部。其中有两部片名的不代表并列,而是代表有两种特色,可以成对观看,二者的优点相映成趣。
● “奥巴马签署行政令禁止学校读效忠宣言”
都不是。1772年,一场空前的危机击中了阿姆斯特丹:一家受人尊敬的荷兰投资银团对不列颠东印度公司(British East India Company)股票的投资变成了一场灾难。
When you are at work, you are supposed to be productive. Otherwise, it's a waste of your time and the company's money. If you are bored and surfing the web most of your work day, you may want to think about looking into job options where you'll get more stimulation and responsibilities.
n. 代表,副手
公民价值观是民主政体最重要的资产。
Shanghai Pudong International Airport reported the lowest punctuality rate last year. Only 52.4% of flights took off on time, with delays averaging 48 minutes.
国际机器人联合会主席Junji Tsuda在他的《全球工业机器人市场》报告中指出,在2017年,全球约有38.7万台工业机器人售出,同比增长31%,创造了500亿美元的收入,而中国则是这一强劲增长背后的关键驱动因素之一。
同样跻身2013年全球最贵城市前十名的还有新加坡、苏黎士、巴黎、委内瑞拉首都加拉加斯和日内瓦。


一个由BuzzFeed News(译者注:类似今日头条的新闻搜集网站)所做的分析揭示了本年度Facebook上流传最广的50条假新闻。他们加起来大约有2150万次的点赞、评论及分享。在这些新闻里,23条和美国政治相关,2条关于女人用她们的阴道作为谋杀用的凶器,还有1条关于一个小丑娃娃其实一直都是个真人。
狗狗雨伞正流行。可爱又有趣的,也非常实用。
A Saudi Woman Who Got Behind the Wheel and Never Looked Back


With the increasing proliferation and sophistication of mobile phones, wearable devices such as smart watches, and sensors that can measure and gather a variety of data, public interest is growing in using consumer electronics to take ownership of personal health and wellness. A 2015 survey found that 66% of Americans age 66 and older want to use mobile technologies to improve their health by receiving medication reminders and tracking diet and nutrition, physical activity, and symptoms.[1

The central bank last year spent more than six months signaling its intent to wean the economy off a third round of bond-buying, and the prospect upset markets at just about every turn. Now it's only in the first stage of that process.
荷兰首相马克?吕特(Mark Rutte)最近由于对安卡拉立场强硬而在民调中排名上升。吕特所属的自由民主人民党(VVD)在民调中略微领先自由党。周二,他将埃尔多安的言论称为“对历史令人恶心的歪曲”,还称“我们不会自甘堕落至这种水平。这完全不可接受”。
而在进口一侧,不论以人民币还是美元计,情况都愈发糟糕。
中国最高纪律监管机构日前表示,去年共有1300名涉嫌经济犯罪的外逃人员回国接受审判,其中腐败官员347人。

Health apps and wearables
Health apps and wearables can unobtrusively gauge physiological and emotional states and collect, quantify, and monitor data regarding a user’s day-to-day behaviors. This “quantified self” can increase users’ self-awareness regarding their behavior and encourage positive changes to their overall health and well-being.[2] These commercially available devices also integrate an array of features to provide motivation through reward systems, opportunities for social in-teraction, tools for self-improvement, and prompts. The novelty, affordability, practicality, and ease of use have resulted in increased consumer enthusiasm and the pervasiveness of these devices.[3,4] With this growing interest in personal health, members of the general public are becoming more involved in monitoring and improving their own health habits.[5-10

Undoubtedly, merely tracking data through a device is not enough to maintain good health-related behaviors long-term, and the software must also incorporate motivational constructs important for the adoption and habituation of behaviors. For instance, a systematic review of studies that considered the use of electronic activity monitor systems found short-term changes in physical activity with self-monitoring, but no demonstration of superiority when the systems were compared with other interventions.[11] Another review of studies on the viability of using mobile technology for measuring and influencing physical activity found that most apps allow users to document their activity, set goals, review real-time feedback, connect to a social support network, and access online expertise.[12] However, less common among these apps were prompts to act and opportunities for problem solving and action planning, which are crucial constructs that translate intention into long-term behavior change.[13]

Sensor technologies
Sensor technologies have begun to enter the telehealth landscape and are primarily focused on continuous monitoring and precise diagnostics to inform management of various health conditions and diseases.[14-17] Sensors can be integrated into a watch or arm band or adhesive bandages and clothing, and then programmed to collect data on cardiac rhythm, heart rate, blood pressure, respiration, oxygen saturation, galvanic skin response, glucose levels, body temperature, body motions, ambient temperature, and global positioning. For health care providers, sensor inputs can permit remote monitoring, real-time teleconferencing, and timely care for patients with chronic diseases. For both patients and clinicians, telehealth supported by sensors can have profound implications. Clinicians can provide timely and patient-centred care to those living at a distance with chronic disease and can coordinate care when multiple providers are involved, reducing costs to the health care system.

A current clinical example is the management of paroxysmal atrial fibrillation with a mobile ECG and app that monitors the patient’s electrical rhythm to detect frequency and patterns of arrhythmias, and may even allow patients to share ultrasound and electrocardiogram data with their health care provider.[18-20] Telemonitoring with sensors can also support self-management of chronic diseases and detect early signs of deterioration in health requiring immediate treatment and advice.[21] Studies to date have demonstrated some clinical promise for the use of home telemonitoring in the context of heart failure and diabetes. A recent Cochrane review found that telemonitoring was an effective way to lower levels of glycated hemoglobin and low-density lipoprotein.[22] Although several studies on heart failure have produced conflicting results regarding the overall benefits of home monitoring,[23-26] systematic reviews have suggested that home telemonitoring reduces all-cause mortality and hospitalizations, and improves quality of life compared with usual care.[22,27] In addition, features such as automated and mobile telemonitoring appear to be more effective compared with other forms of home telemonitoring.[27]

Further studies are needed to determine how home health monitoring can improve patient safety during the transition from acute care to community care, and to examine the impact of home monitoring on health care costs. TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), an initiative of the University of British Columbia and Vancouver Coastal Health, is seeking to do this with prospective trials designed to uncover how telemonitoring can support the safety of heart failure patients discharged from hospital to home.[28]

Mobile apps, wearables, and sensors in the clinical setting
Even though mobile apps, wearables, and sensor technologies are promising, further research is needed to validate their use and long-term impact.[29] This research will require the collaboration of clinicians, health researchers, engineers, and computer scientists.[30] Understanding the possible risks of using these technologies, from physiological harm to breaching of privacy and confidentiality with insecure devices, and how to mitigate any risks is also important. Other important issues to consider include patient anxiety with overuse of technologies, health data piracy, self-diagnosis resulting from overreliance on self-monitoring, and patients not seeking help appropriately. These technologies should be used only as complementary tools in the treatment and prevention of health conditions and disease and should not be used in isolation by patients who self-diagnose and self-manage without consulting a health professional. 

第三季度摄影师的工作增长了大约22%。报告的作者将这一增长归因于雇佣者“最终理解了他们的登录页面的高质量图片的重要性”。通过雇用受过培训的有创造力的专业人员来扩大提升网站知名度也是这一排行榜上的一个常在的主题。

Instant Heart Rate by Azumio.[31] A free app downloadable to both Apple and Android operating systems that measures heart rate and displays a monitoring strip. As well as helping users accurately track their heart rates, the app is capable of detecting irregular rhythms when palpitations occur. 

Sleep Time by Azumio.[32] A free app that monitors sleep patterns, sleep efficiency, and also acts as an alarm clock. Users can know how often they go into light and deep sleep, and recognize how much of these types of sleep will be necessary for them to feel rested, thereby quantifying the amount of true sleep they need and not just how long they should stay in bed. 

Bellybio Interactive Breating by RelaxLine.[33] A free app that helps users pace their breathing to achieve calmness. Placing the mobile phone against the abdomen, users can follow the sounds emitted to practise deep, abdominal breathing using this simple yet surprisingly effective tool. 

Thirty-six Chinese brands have made it onto the list this year. Among them, eight are in the top 100, including the State Grid Corporation of China (36), the Industrial and Commercial Bank of China (ICBC) (40), Tencent (43), China Central Television (CCTV) (62), Haier (76), China Mobile (79), Huawei (81) and Lenovo (90).
severe

She has also performed on Jimmy Kimmel and The Ellen Show - not bad for someone who hasn't even hit adolescence.
vi. 自制
“有个员工的父母跟公司联系,告诉我们说,他们的儿子辞职了。”
1. 仅根据薪水选工作
单词celebrity 联想记忆:
委内瑞拉政府一年前关闭了所有边境口岸,以打击长达1378英里(2219公里)边境沿线的走私活动。政府抱怨说,正是因为投机者在委内瑞拉购买了补贴的食品和汽油,并将他们带到哥伦比亚高价出售造成的短缺。

Discernment to determine whether a particular app, wearable, or sensor can be effective.
Expertise and experience to guide patients on the use of technology.
Partnership with patients in pursuit of optimal health through technology use.
Trials to closely monitor benefits and drawbacks.
Humility to recognize that patients may know and invest much more time than physicians in looking for these tools.34

Conclusions
Based on today’s rapid pace of development and public enthusiasm for the technology marketplace, health apps, wearables, and sensors will soon become integral to our patients’ pursuits of good health and will need to be integrated in clinical practice. Physicians must be active agents in these evolutionary times, guiding patients, advocating for evidence to support the use of technologies, and participating in the development and incorporation of technology in patient wellness journeys. Through clinical stewardship and partnership with patients, physicians can use their expertise and experience to guide the growth of innovations into mainstream health care.

Competing interests
Dr Ho receives no personal financial compensation as the principal investigator of TEC4Home (Telehealth for Emergency-Community Continuity of Care Connectivity via Home Tele-monitoring), a project funded by a Canadian Institutes of Health Research grant. This grant is matched by the Michael Smith Foundation for Health Research and the BC Ministry of Health, with additional support provided by TELUS Health and Sentrian. TELUS Health, Cisco, and Avizia have also provided equipment for display in Dr Ho’s Demonstration and Simulation Studio for Health (DaSSH) at UBC. Mr Yao and Dr Lauscher have no competing interests to declare.


建材市场价格稳定运行 市场成交一般


References

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2. Swan M. Emerging patient-driven health care models: An examination of health social networks, consumer personalized medicine and quantified self-tracking. Int J Environ Res Public Health 2009;6:492-525.

3. Gao Y, Li H, Luo Y. An empirical study of wearable technology acceptance in healthcare. Ind Manag Data Syst 2010;115:1704-1723.

4. Kim KJ, Shin DH. An acceptance model for smart watches: Implications for the adoption of future wearable technology. Internet Res 2015;25:527-541.

5. West JH, Hall PC, Hanson CL, et al. There’s an app for that: Content analysis of paid health and fitness apps. J Med Internet Res 2012;14:e72.

6. Abroms LC, Padmanabhan N, Thaweethai L, Phillips T. iPhone apps for smoking cessation: A content analysis. Am J Prev Med 2011;40:279-285.

7. Cowan LT, Van Wagenen SA, Brown BA, et al. Apps of steel: Are exercise apps providing consumers with realistic expectations? A content analysis of exercise apps for presence of behavior change theory. Health Educ Behav 2013;40:133-139.

8. Azar KM, Lesser LI, Laing BY, et al. Mobile applications for weight management. Am J Prev Med 2013;45:583-589.

9. Breland JY, Yeh VM, Yu J. Adherence to evidence-based guidelines among diabetes self-management apps. Transl Behav Med 2013;3:277-286.

10. Lyons EJ, Lewis ZH, Mayrsohn BG, Rowland JL. Behavior change techniques implemented in electronic lifestyle activity monitors: A systematic content analysis. J Med Internet Res 2014;16:e192.

11. Lewis ZH, Lyons EJ, Jarvis JM, Baillargeon J. Using an electronic activity monitor system as an intervention modality: A systematic review. BMC Public Health 2015;15:585.

12. Bort-Roig J, Gilson ND, Puig-Ribera A, et al. Measuring and influencing physical activity with smartphone technology: A systematic review. Sports Med 2014;44:671-686.

13. Rhodes RE, Yao CA. Models accounting for intention-behavior discordance in the physical activity domain: A user’s guide, content overview, and review of current evidence. Int J Behav Nutr Phys Act 2015;12:1-14.

14. Chen M, Gonzalez S, Vasilakos A, et al. Body area networks: A survey. Mob Networks Appl 2011;16:171-193.

15. Appelboom G, Camacho E, Abraham ME, et al. Smart wearable body sensors for patient self-assessment and monitoring. Arch Public Health 2014;72:28.

16. Chan M, Estève D, Fourniols JY, et al. Smart wearable systems: Current status and future challenges. Artif Intell Med 2012;56:137-156.

17. Alemdar H, Ersoy C. Wireless sensor networks for healthcare: A survey. Comput Networks 2010;54:2688-2710.

18. Haberman ZC, Jahn RT, Bose R, et al. Wireless smartphone ECG enables large-scale screening in diverse populations. J Cardiovasc Electrophysiol 2015;26:520-526.

19. Ferdman DJ, Liberman L, Silver ES. A smartphone application to diagnose the mechanism of pediatric supraventricular tachycardia. Pediatr Cardiol 2015;36:1452-1457.

20. Baquero GA, Banchs JE, Ahmed S, et al. Surface 12 lead electrocardiogram recordings using smart phone technology. J Electrocardiol 2015;48:1-7.

21. Wootton R. Twenty years of telemedicine in chronic disease management—An evidence synthesis. J Telemed Telecare 2012;18:211-220.

22. Flodgren G, Rachas A, Farmer A, et al. Interactive telemedicine: Effects on professional practice and health care outcomes. Cochrane Database System Rev 2015;(9):CD002098.

23. Mortara A, Pinna GD, Johnson P, et al. Home telemonitoring in heart failure patients: The HHH study (Home or Hospital in Heart Failure). Eur J Heart Fail 2009;11:312-318.

24. Dar O, Riley J, Chapman C, et al. A randomized trial of home telemonitoring in a typical elderly heart failure population in North West London: Results of the Home-HF study. Eur J Heart Fail 2009;11:319-325.

25. Chaudhry SI, Mattera JA, Curtis JP, et al. Telemonitoring in patients with heart failure. N Engl J Med 2010;363:2301-2309.

26. Koehler F, Winkler S, Schieber M, et al. Impact of remote telemedical management on mortality and hospitalizations in ambulatory patients with chronic heart failure: The Telemedical Interventional Monitoring in Heart Failure study. Circulation 2011;123:1873-1880.

27. Kitsiou S, Pare G, Jaana M. Effects of home telemonitoring interventions on patients with chronic heart failure: An overview of systematic reviews. J Med Internet Res 2015;17:e63.

28. TEC4Home Healthcare Innovation Community. Supporting heart failure patient transitions from acute to community care with home telemonitoring technology: A protocol for a provincial randomized controlled trial (TEC4Home). JMIR Res Protoc 2016;5:e198. 

29. Yao C, Ho K. Mobile sensors and wearable technologies. In: Amelung VE, Stein V, Goodwin N, et al., editors. Handbook integrated care. Cham, Switzerland: Springer; 2017.

30. Ho K, Borycki E, Kushniruk A, et al. The health perspective in using digital media for health and wellness. Presented at the IEEE International Digital Media Industry Forum, Boston, MA, 4-6 July 2016.

31. Azumio Inc. Instant heart rate. Accessed 28 August 2017. www.azumio.com/s/instantheartrate/index.html. 

32. Azumio Inc. Sleep time. Accessed 28 August 2017. www.azumio.com/s/sleeptime/index.html. 

33. RelaxLine. BellyBio. Accessed 28 August 2017. https://itunes.apple.com/ca/app/bellybio-interactive-breathing/id353763955?mt=8.

34. Ho K. How health information technologies are enhancing health of patients and their doctors. Presentation at the Alberta Medical Association 2015 Spring Representatives Forum, Edmonton, AB, 13 March 2015.


I've seen managers not hire a woman because the environment is mostly male, and they're worried that no matter how smart or talented she is, she won't fit in.
He and his girlfriend wrote to each other when he was studying science, he said.They did eventually marry and have four children.
Yes Man is a heartwarming blockbuster that explores what would happen if you answered "yes" to every question in your life. Jim Carrey's character takes on this challenge and ends up learning Korean, taking flying lessons, and getting promoted. He goes from being a pessimistic divorced man to an exciting trendsetter and finds a new girlfriend in the process. It might sound like fiction, but this movie is loosely based on a memoir of the same name by freelance radio producer Danny Wallace.
I wonder if the Pelicans are in that position, too. It looks like their highest Brow-era pick will be Buddy Hield. That's not optimal.
单词affection 联想记忆:
10月份,CPI环比下降了0.1%,9月份则环比上涨了0.7%。
Bank of China followed the trend, with profits up only 1.3 per cent and ROAA declining by 0.1 percentage points.
银行家们表示,音乐流媒体服务Spotify计划最早第四季度在纽约证券交易所(NYSE)直接上市其现有的非公开发行股票,而不走正式的IPO程序,而其他大型知名科技公司则被视为更有可能在2018年上市。
但是Gitanjali的便携发明,可以通过一个与手机app连接的传感器,就得出一个确切、及时的分析。
You'd love to know the balance of forces that shape and move your ponytail, right? That's why Joseph Keller, Raymond Goldstein, Patrick Warren and Robin Ball received this igNOMINIOUS prize!

Kendall Ho, MD, FRCPC, Christopher Yao, MSc, Helen Novak Lauscher, PhD. Part 2: Health apps, wearables, and sensors: The advancing frontier of digital health. BCMJ, Vol. 59, No. 10, December, 2017, Page(s) 503-506 - Clinical Articles.



Above is the information needed to cite this article in your paper or presentation. The International Committee of Medical Journal Editors (ICMJE) recommends the following citation style, which is the now nearly universally accepted citation style for scientific papers:
Halpern SD, Ubel PA, Caplan AL, Marion DW, Palmer AM, Schiding JK, et al. Solid-organ transplantation in HIV-infected patients. N Engl J Med. 2002;347:284-7.

About the ICMJE and citation styles

The ICMJE is small group of editors of general medical journals who first met informally in Vancouver, British Columbia, in 1978 to establish guidelines for the format of manuscripts submitted to their journals. The group became known as the Vancouver Group. Its requirements for manuscripts, including formats for bibliographic references developed by the U.S. National Library of Medicine (NLM), were first published in 1979. The Vancouver Group expanded and evolved into the International Committee of Medical Journal Editors (ICMJE), which meets annually. The ICMJE created the Import growth lifted year-on-year to a pace of 17.7 per cent for the period, up from 17.2 per cent a month earlier and beating an expected rate of 11.3 per cent. to help authors and editors create and distribute accurate, clear, easily accessible reports of biomedical studies.

Everybody has heard by now that health care companies are promising hunting grounds for job seekers, and the New Year will see hiring perk up elsewhere, too.
全国工商联汽车经销商会数据显示,自2014年进口现代中国经销商网络已经缩减了一半。
比特币发展势头强劲的另一个指标是,接受比特币的主流企业数量增加。2014年,微软、贝宝、戴尔以及Dish Network等企业宣布,自身一系列产品接受比特币付款。此前已有塔吉特(该公司接受能以比特币购买的Gyft)、Overstock.com以及WordPress等公司接受比特币。就连《财富》出版商——时代公司,也开始接受比特币杂志订阅。去年,雅虎还将比特币加入其雅虎财经跟踪网站,令比特币更显正统。谷歌财经也很快依样画葫芦。雅虎发言人向CoinDesk网站表示:“接受比特币越来越普遍,我们觉得这与我们行业、我们用户切身相关。”假如雅虎很快更大力押宝比特币——不论是收购比特币新创企业,还是宣布其他动作——都别太惊讶,因为雅虎首席执行官玛丽莎o梅耶尔正努力使这家止步不前的搜索巨头变得更时髦。
但是,斯蒂文森称“这或许反映出美国在保护本国钢铁制造商方面比欧盟更大胆”。

英国剑桥大学Judge商学院(Judge Business School)排名上升速度最快,今年上升19位,名列第29位,这得益于其在高管MBA排名中的出色表现(该学院今年首次参与此项排名)。华威商学院(Warwick Business School)重返榜单前20名(位列第19),该校去年未参加管理硕士排名。

  • Only the first three authors are listed, followed by "et al."
  • 带动环渤海地区协同发展 京津冀城市群:互联互通深度融合
  • 多地下调公积金贷款利率 楼市全面回暖暂时很难


6.The Stock Market Plunge
tunnel

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